Modulation of Angiogenesis by Omega-3 Polyunsaturated Fatty Acids is Mediated by Cyclooxygenases, Szymczak, Murray & Petrovic, Blood 2008;111 (7): 3514-3521.
N-3 Fatty Acids, Cancer and Cachexia: A Systematic Review of the Literature, Colomer, Moreno-Nogufeira, Garcia-Luna,
et al., Br. J. Nutr. 2007; 975: 823-831.
Dietary Omega-3 Fatty Acids, Cyclooxygenase-2 Genetic Variation, and Aggressive Prostate
Cancer Risk. Fradet , Cheng, Casey &Witte, Clin Cancer Res. 2009; 15 (7): 2559-2566.
Prevention and Treatment of Pancreatic
Cancer by Curcumin in Combination with Omega-3 Fatty Acids, Swamy, Citineni, et al, Nutr. Cancer 2008; 60 Suppl. 1: 81-89.
Omega
3 Fatty Acids: Biological Activity and Effects on Human Health, La Guardia, Giammanco, Di Majo, et al., Panminerva Med. 2005; 47 (4):245-257.
Effect of Eicosapentaenoic Acid, Protein and Amino Acids on Protein Synthesis and Degradation in Skeletal Muscle of
Cachectic Mice, Smith, Greenberg & Tisdale, Br. J. Cancer 2004; 91 (2): 408-412.
Role of Omega-3 Fatty Acid Supplementation
in Inflammation and Malignancy, Jho, Cole, Lee & Espat, Integr. Cancer Ther. 2004; (2): 98-111.
Cytotoxic Drugs Efficacy
Correlates with Adipose Tissue Docosahexaenoic Acid Level in Locally Advanced Breast Carcinoma, Bougnoux, Germain, Chajes, et al., Br. J. Cancer 1999; 79 (11-12): 1765-1769.
Complementary Actions of Docosahexaenoic Acid and Genistein on COX-2, PGE2 and
Invasiveness in MDA-MB-231 Breast Cancer Cells, Horia E, Watkins BA. Carcinogenesis 2007; 28 (4): 809-815.
n-3 PUFAs
Modulate T-cell Activation via Protein Kinase C-alpha and -epsilon and the NF-kappaB Signaling Pathway, Denys , Hichami & Khan, J. Lipid Res. 2005; 46 (4): 752-758.
n-3 Fatty Acids, Inflammation, and Immunity: Relevance to Post-surgical and
Critically Ill Patients, Calder, Lipids 2004; 39 (12): 1147-1161.
Impact of Post-operative Omega-3 Fatty Acid-supplemented Parenteral Nutrition on Clinical Outcomes and Immuno-modulations in Colorectal Cancer Patients, Liang, Wang, Ye, et al., World J. Gastroenterol. 2008; 14 (15): 2434-2439.
An Inverse Relationship Between Plasma n-3 Fatty Acids and C-reactive Protein in Healthy Individuals, Micallef,
Munro & Garg, Eur. J. Clin. Nutr. 2009; advance online publication 8 April 2009; doi: 10.1038/ejcn.2009.20
High Omega-3 Fat
Intake Improves Insulin Sensitivity and Reduces CRP and IL6, But Does Not Affect Other Endocrine Axes in Healthy Older Adults, Tsitouras,
Gucciardo, Salbe, et al., Horm. Metab. Res. 2008; 40 (3): 199-205.
Dietary Omega-3 Fatty Acids, Cyclo-oxygenase-2 Genetic Variation,
and Aggressive Prostate Cancer Risk, Fradet, Cheng, Casey & Witte, Clin, Cancer Res. 2009; 15 (7): 2559-2566.
The Potential
for Treatment with Dietary Long-chain Polyunsaturated n-3 Fatty Acids During Chemotherapy, Biondo, Brindley, Sawyer & Field, J.
Nutr. Biochem. 2008; 1912: 787-796.
Chemoprotective and Renal Protective Effects for Docosahexaenoic Acid (DHA): Implications
of CRP and Lipid Peroxides, Elmesery, et al., Cell Div. 2009; 4 (1): 6.
Omega-3 Fatty Acids Can Improve Radioresponse Modifying
Tumor Interstitial Pressure, Blood Rheology and Membrane Peroxidability, Baronzio, Freitas, Griffini et al., Anticancer
Res. 1994; 14 (3A): 1145-1154
Neuroblastoma Cell Death in Response to Docosahexaenoic acid: Sensitization to Chemotherapy
and Arsenic-induced Oxidative Stress, Lindskog, Gleissman, Ponthan et al., Int. J. Cancer 2006; 118 (10): 2584-2593.
Differential
Sensitization of Cancer Cells to Doxorubicin by DHA: A Role for Lipoperoxidation, Maheo, Vibet, Steghens et al., Free Radic. Biol.
Med. 2005; 39 (6): 742-751.
Cytotoxic Drugs Efficacy Correlates with Adipose Tissue Docosahexaenoic Acid Level in Locally Advanced
Breast Carcinoma, Bougnoux, Germain, Chajes et al., Br. J. Cancer 1999; 79 (11-12): 1765-1769.
Sensitization by Docosahexaenoic
Acid (DHA) of Breast Cancer Cells to Anthracyclines Through Loss of Glutathione Peroxidase (GPx1) Response, Vibet, Goupille, Bougnoux,
et al., Free Radic. Biol. Med. 2008; 44 (7): 1483-1491.
Phase II Study of High-dose Fish Oil Capsules for Patients with
Cancer-related Cachexia, Burns, Halabi, Clamon, et al., Cancer 2004; 101: 370-378.
The Effect of Dietary Omega-3 Polyunsaturated
Fatty Acids on T-lymphocyte Subsets of Patients with Solid Tumors, Gogos, Ginopoulos, Zoumbos, et al., Cancer Detect. & Prev. 1995;
19 (5): 415-417.
Effect of a Protein and Energy Dense N-3 Fatty Acid Enriched Oral Supplement on Loss of Weight and Lean Tissue
in Cancer Cachexia: A Randomised Double Blind Trial, Fearon, Von Meyenfeldt, Moses, et al., Gut 2003; 52 (10): 1479-1486.
Modulation
of Inflammation and Cytokine Production by Dietary (n-3) Fatty Acids, Blok, Katan & van der Meer, J. Nutr. 1996; 126 (6):
1515-1533.
Effect of Dietary Fish Oil on Development and Selected Functions of Murine Inflammatory Macrophages, Hubbard, Somers
& Eriskson, J. Leukoc. Biol. 1991; 49: 592.
Antitumor Activity of Fish Oils Against Human Lung Cancer is Associated with Altered Formation of PGE2 and PGE3 and Regulation of Akt Phosphorylation, Yang, Chan, Cartwright, et al., 5th AACR Int. Conf. Frontiers Cancer Prev. Res. 2006.
Dietary Omega-3 Polyunsaturated Fatty Acids Plus Vitamin E Restore Immunodeficiency and Prolong Survival
for Severely Ill Patients with Generalized Malignancy: A Randomized Control Trial, Gogos, Ginopoulos, Salsa, et al., Cancer 1998;
82 (2): 395-402.