Pomegranate Extract Inhibits Androgen-independent Prostate Cancer Growth Through a Nuclear Factor Kappa-B dependent Mechanism, Rettig, et al., Mol. Cancer Ther. 2008; 7 (9): 2662-2671.
In vitro Anti-proliferative, Apoptotic and Antioxidant Activities of
Punicalagin, Ellagic Acid and a Total Pomegranate Tannin Extract are Enhanced in Combination with other Polyphenols as Found in Pomegranate
Juice, Seeram, Adams, Henning, et al., J. Nutr. Biochem. 2005; 16 (6): 360-367.
Pomegranate Polyphenols Down-regulate Expression
of Androgen-synthesizing Genes in Human Prostate Cancer Cells Over-expressing the Androgen Receptor, Young, Hong, Seeram & Heber,J. Nutr. Biochem. 2008; 19 (12): 848-855.
Ellagic Acid Induces Apoptosis Through Inhibition of Nuclear Factor Kappa B in Pancreatic
Cancer Cells, Edderkaoui, Odinokova, Ohno, et al., World J. Gastroenterol. 2008; 14 (23): 3672-3680.
Combined Inhibition of PDGF
and VEGF Receptors by Ellagic Acid, a Dietary-derived Phenolic Compound, Labrecque, Lamy, Chapus, et al.,Carcinogenesis 2005; 26 (4):
821-826.
In vitro Anti-proliferative Activities of Ellagic Acid, Losso, Bansode, Trappey, et al., J. Nutr. Biochem.2004;15 (11): 672-678.
Support Ellagic Acid Therapy in Patients with Hormone Refractory Prostate Cancer (HRPC) on Standard Chemotherapy
Using Vinorelbine and Estramustine Phosphate, Falsaperla, Morgia, Tartarone, et al., Eur. Urol. 2005; 47 (4): 449-454.
Phase
II Study of Pomegranate Juice for Men with Rising Prostate-Specific Antigen Following Surgery or Radiation for Prostate Cancer, Pantuck,
Leppert, Zomorodian, et al., Clin. Cancer Res. 2006; 12 (13): 4018-4026.